Fluticasone propionate - Bio-X ™

CAS: 80474-14-2

Ref. 3D-BF161262

Product Information

• Name: Fluticasone propionate - Bio-X ™
• Synonyms: (6α,11β,16α,17α)-6 ,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1 ,4-diene-17-carbothioic acid S-(fluoromethyl) ester Cutivate Flixonase Fluticasone Fluticasone propionate
• Brand: Biosynth
• Description: As a synthetic trifluorinated glucocorticoid receptor agonist, Fluticasone exhibits anti-inflammatory properties. When binding to and activating glucocorticoid receptors, Fluticasone initiates the activation of lipocortin which inhibits cytosolic phospholipase A2. Consequently, the cascade of inflammatory mediator synthesis reactions are inactivated and the production of inflammatory cells namely mast cells, dendritic cells, macrophages and eosinophils and the cytokines that they produce are greatly reduced.It is this anti-inflammatory role which has enabled Fluticasone to successfully treat conditions such as asthma, emphysema, allergic rhinitis and atopic dermatitis. It has also been seen to increase anti-inflammatory effects of annexoin-1 and mitogen-activated kinase phosphatase-1; reduce mucus gland secretions and increase the number of beta-2 receptors on smooth muscles of the airways.Fluticasone is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Chemical properties

• Molecular weight: 500.57 g/mol
• Formula: C₂₅H₃₁F₃O₅S
• Purity: Min. 95%
• Color/Form: White/Off-White Solid