Product Information
- 2-Oxo-2-(p-tolyl)ethyl 3-(2,4-dinitrobenzamido)benzoateFM19G11
Inhibitor of HIF1-α transcription factor and repressor of HIF1-α-regulated genes in adult and embryonic stem cell models as well as in tumoral cell lines. FM19G11 inhibits the expression of undifferentiating factors Oct4, Sox2, Nanog, and Tgf-α at transcriptional and protein level. FM 19G11 affects also epigenetic events by reducing histone acetylation and leading to repression of p300, a HIF-transcription activation co-factor.
Chemical properties
Technical inquiry about: 3D-BF168364 FM 19G11
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