Product Information
Name:GSK 583
Synonyms:
- 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine
Brand:Biosynth
Description:A potent and selective inhibitor of cell death-inducing kinase RIP2 (IC50 = 5 nM). Reduces release of pro-inflammatory cytokines. Inhibits production of TNF-α and IL-6 in intestinal explants from patients with Crohn's disease and ulcerative colitis.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:398.46 g/mol
Formula:C20H19FN4O2S
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C20H19FN4O2S/c1-20(2,3)28(26,27)13-5-7-16-14(11-13)17(8-9-22-16)23-19-15-10-12(21)4-6-18(15)24-25-19/h4-11H,1-3H3,(H2,22,23,24,25)
InChI key:InChIKey=XLOGLWKOHPIJLV-UHFFFAOYSA-N
SMILES:CC(C)(C)S(=O)(=O)c1ccc2nccc(Nc3n[nH]c4ccc(F)cc34)c2c1
Technical inquiry about: GSK 583
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