Estimated delivery in United States, on Monday 16 Dec 2024
Product Information
Name:
GNE 781
Synonyms:
- 3- [7- (difluoromethyl) - 3
- 4- dihydro- 6- (1- methyl- 1H- pyrazol- 4- yl) - 1(2H) - quinolinyl] - 1
- 4
- 6
- 7- tetrahydro- N- methy l- 1- (tetrahydro- 2H- pyran- 4- yl) -5H- Pyrazolo[4
- 3- c] pyridine- 5- carboxamide
Description:
A selective inhibitor of the bromodomain of Cyclic adenosine monophosphate Response Element Binding protein Binding Protein (CREBBP or CBP) with anti-tumoral activity. The CBP inhibition regulates oncogene MYC and impairs differentiation of regulatory T cells.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
525.59 g/mol
Formula:
C27H33F2N7O2
Purity:
Min. 95%
InChI:
InChI=1S/C27H33F2N7O2/c1-30-27(37)34-9-5-23-22(16-34)26(32-36(23)19-6-10-38-11-7-19)35-8-3-4-17-12-20(18-14-31-33(2)15-18)21(25(28)29)13-24(17)35/h12-15,19,25H,3-11,16H2,1-2H3,(H,30,37)
InChI key:
InChIKey=CQCWHSDMJBAGDC-UHFFFAOYSA-N
SMILES:
CNC(=O)N1CCc2c(c(N3CCCc4cc(-c5cnn(C)c5)c(C(F)F)cc43)nn2C2CCOCC2)C1
MDL:
Melting point:
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EINECS:
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HS code:
Technical inquiry about: 3D-BG166815 GNE 781
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