GC376 sodium

CAS: 1416992-39-6

Ref. 3D-BG167367

Product Information

• Name: GC376 sodium
• Synonyms: Sodium (2S)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate
• Brand: Biosynth
• Description: GC 376 is an inhibitor of the main protease Mpro (3CLpro) in coronaviruses as well as picornaviruses. This broad-spectrum antiviral compound has been used as investigational veterinary drug for treatment of feline infectious peritonitis virus (FIPV) infections. Recent studies also showed that GC 376 inhibits the main protease Mpro (3CLpro) from SARS-CoV-2 with IC50 of 0.03 μM and EC50 of 3.37 μM.

Chemical properties

• Molecular weight: 507.53 g/mol
• Formula: C₂₁H₃₀N₃NaO₈S
• Purity: Min. 95 Area-%
• Color/Form: White Powder