Indomethacin - Bio-X ™

CAS: 53-86-1

Ref. 3D-BI166166

Product Information

• Name: Indomethacin - Bio-X ™
• Synonyms: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid, 1-(4-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid, 1-(4-Chlorobenzoyl)-5-Methoxy-2-Methylindol-3-Ylacetic Acid, 1-(4-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid, 1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid, 1-(p-Chlorobenzoyl)-2-methyl-5-methoxyindole-3-acetic acid, 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetic acid, 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid, 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid, 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid, Aconip, Amuno, Argun, Artracin, Artrinovo, Artrivia, Bonidin, Bonidon Gel, Catlep, Chibro-Amuno, Chrono-Indicid, Chrono-Indocid 75, Confortid, Dolcidium, Dolcidium PL, Dolovin, Durametacin, Elmetacin, Endol, Flam, Globa, Idomethine, Imbrilon, Inacid, Indacin, Indo-Phlogont, Indo-Rectolmin, Indo-Tablinen, IndoRich, Indocid, Indocid (pharmaceutical), Indocin, Indocine, Indocollyre, Indole-3-acetic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-, Indomecol, Indomed, Indomee, Indometacin, Indometacina, Indometacine, Indomethacin Crystalline, Indomethacin Methanol Solution, Indomethacin Powder, Indomethacin Usp, Indomethacine, Indomethine, Indomod, Indonol, Indoptic, Indoptol, Indorektal, Indoxen, Indren, Inflazon, Infrocin, Innamit, Inteban, Inteban SP, Lausit, Metacen, Metartril, Methazine, Metindol, Mezolin, Microcid, Mikametan, Mobilan, N-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid, Nsc 77541, Reumacide, Rheumacin LA, Sadoreum, Tannex, Vital Vitacid, Vonum, [1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid, {1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetate, α-[1-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolyl]acetic acid
• CAS: 53-86-1

Description

Indomethacin is a nonsteroidal anti-inflammatory drug that inhibits the production of prostaglandin PGE2. It is used to treat pain, fever, and inflammation. Indomethacin's mechanism of action is not well understood, but it may be due to interference with the ability of PMNs to bind to the surface of bacteria or to release reactive oxygen species. The drug has been shown to reduce mitochondrial membrane potential in mammalian cells, leading to apoptosis. This effect on mitochondria may also contribute to Indomethacin's anti-inflammatory effects. Indomethacin is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

• Brand: Biosynth

Chemical properties

• Molecular weight: 357.79 g/mol
• Formula: C₁₉H₁₆ClNO₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)
• InChI key: InChIKey=CGIGDMFJXJATDK-UHFFFAOYSA-N
• SMILES: COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1