Product Information
- N- (3- Fluorophenyl) - 2
- 4- dihydro- 6
- 7- dimethoxy-indeno[1
- 2- c] pyrazol- 3- amineRWJ 540973
Selective inhibitor of the platelet derived growth factor receptor PDGFRβ with IC50 value of 4.2 nM. JNJ 10198409 inhibits the PDGFRβ kinase activity and its downstream signalling leading to anti-proliferative and anti-angiogenic effects, which were confirmed in various tumoral cell lines.
Chemical properties
Technical inquiry about: 3D-BJ163192 JNJ 10198409
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