Product Information
Name:JNJ 38877605
Synonyms:
- 6-(Difluoro(6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)quinoline
Brand:Biosynth
Description:Potent inhibitor of c-Met catalytic activity. Selective over other tyrosine and serine-threonine kinases (600-fold selectivity). Ability to block constitutive or HGF-stimulated phosphorylation of c-Met demonstrated in vitro. JNJ 38877605 reduces radiation-induced invasion, apoptosis and proliferation of cancer cells in vitro.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:377.12005
Formula:C19H13F2N7
Purity:Min. 95%
Color/Form:Solid
InChI:InChI=1S/C19H13F2N7/c1-27-11-13(10-23-27)16-6-7-17-24-25-18(28(17)26-16)19(20,21)14-4-5-15-12(9-14)3-2-8-22-15/h2-11H,1H3
InChI key:InChIKey=JRWCBEOAFGHNNU-UHFFFAOYSA-N
SMILES:Cn1cc(-c2ccc3nnc(C(F)(F)c4ccc5ncccc5c4)n3n2)cn1
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