Product Information
Name:MRTX849
Synonyms:
- Adagrasib
Brand:Biosynth
Description:MRTX849 is a small molecule inhibitor, which is derived through rational drug design targeting specific oncogenic mutations. It acts as a covalent inhibitor that selectively targets the KRAS G12C mutation, a prevalent alteration in various cancers such as non-small cell lung cancer and colorectal cancer. The mode of action involves binding to the mutated KRAS G12C protein, locking it in an inactive GDP-bound state, thereby inhibiting downstream signaling pathways crucial for tumor cell proliferation and survival.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:604.12 g/mol
Formula:C32H35ClFN7O2
Purity:Min. 95%
Technical inquiry about: MRTX849
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