Estimated delivery in United States, on Tuesday 10 Dec 2024
Product Information
Name:
PF 05085727
Description:
Inhibitor of cGMP-dependent phosphodiesterase 2A (PDE2A) with IC50 = 2 nM and has higher affinity over other phosphodiesterases (>500-fold). Increases cGMP in rodent brain in vivo. Reverses anxiolytic behaviour, enhances performance of new object recognition and social recognition tasks. Potentiates NMDA signalling and reverses behavioural effects of NMDA antagonists.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
413.4 g/mol
Formula:
C20H18F3N7
Purity:
Min. 95%
Color/Form:
White To Off-White Solid
InChI:
InChI=1S/C20H18F3N7/c1-28-17(12-4-6-13(7-5-12)20(21,22)23)14(10-26-28)16-15-18(29(2)27-16)24-11-25-19(15)30-8-3-9-30/h4-7,10-11H,3,8-9H2,1-2H3
InChI key:
InChIKey=SHAVEYUXRBIMLA-UHFFFAOYSA-N
SMILES:
Cn1ncc(-c2nn(C)c3ncnc(N4CCC4)c23)c1-c1ccc(C(F)(F)F)cc1
MDL:
Melting point:
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EINECS:
Merck:
HS code:
Technical inquiry about: 3D-BP165159 PF 05085727
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