Product Information
Name:PD 98059
Synonyms:
- 2-(2-Amino-3-methoxyphenyl)-4H-chromen-4-one
Brand:Biosynth
Description:MAP kinase kinase (MEK) inhibitor. Binds to MEK-1, preventing phosphorylation and activation by Raf or MEK kinase. PD 098059 enhances self-renewal in stem cells. Has anti-growth and anti-proliferative effects on AML cells. Anti-apoptotic effect on AML cells observed in synergy with Nutlin-3a.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:267.28 g/mol
Formula:C16H13O3N
Purity:Min. 95%
Color/Form:Off-White Powder
InChI:InChI=1S/C16H13NO3/c1-19-14-8-4-6-11(16(14)17)15-9-12(18)10-5-2-3-7-13(10)20-15/h2-9H,17H2,1H3
InChI key:InChIKey=QFWCYNPOPKQOKV-UHFFFAOYSA-N
SMILES:COc1cccc(-c2cc(=O)c3ccccc3o2)c1N
Technical inquiry about: PD 98059
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