PD 98059

CAS: 167869-21-8

Ref. 3D-BP34124

Product Information

• Name: PD 98059
• Synonyms: 2-(2-Amino-3-methoxyphenyl)-4H-chromen-4-one
• Brand: Biosynth
• Description: MAP kinase kinase (MEK) inhibitor. Binds to MEK-1, preventing phosphorylation and activation by Raf or MEK kinase. PD 098059 enhances self-renewal in stem cells. Has anti-growth and anti-proliferative effects on AML cells. Anti-apoptotic effect on AML cells observed in synergy with Nutlin-3a.

Chemical properties

• Molecular weight: 267.28 g/mol
• Formula: C₁₆H₁₃O₃N
• Purity: Min. 95%
• Color/Form: Off-White Powder
• InChI: InChI=1S/C16H13NO3/c1-19-14-8-4-6-11(16(14)17)15-9-12(18)10-5-2-3-7-13(10)20-15/h2-9H,17H2,1H3
• InChI key: InChIKey=QFWCYNPOPKQOKV-UHFFFAOYSA-N
• SMILES: COc1cccc(-c2cc(=O)c3ccccc3o2)c1N