Product Information
Name:RCM 1
Synonyms:
- 2-[2-Oxo-2-(2-thienyl)ethyl]sulfanyl-4,6-bis(2-thienyl)pyridine-3-carbonitrile
Brand:Biosynth
Description:Inhibitor of the Forkhead box M1 (FOXM1), an oncogene and a transcription factor regulating cell cycle progression, DNA damage repair and cell renewal. RCM 1 weakens the FOXM1 activity by inhibiting its nuclear localisation and increasing its degradation in proteasomes. The compound showed potential for asthma treatment since it inhibited goblet cell metaplasia and IL-13 signalling in mice.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:424.59 g/mol
Formula:C20H12N2OS4
Purity:Min. 95%
Color/Form:Solid
InChI:InChI=1S/H3N/h1H3
InChI key:InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
SMILES:N#Cc1c(-c2cccs2)cc(-c2cccs2)nc1SCC(=O)c1cccs1
Technical inquiry about: RCM 1
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