Product Information
- SU02684'- [[[1- (cyclopropylcarbonyl ) - 1
- 2
- 3
- 4- tetrahydro- 7- quinolinyl] amino] sulfonyl] -[1
- 1'- Biphenyl] - 3- carboxamid e
Inhibitor of 8-oxoguanine DNA glycosylase OGG1 with IC50 of 0.059 μM and excellent specificity over other DNA repair enzymes. OGG1 and its substrate 8-oxoguanine are involved in mutagenesis, genotoxicity, inflammation and cancer. The compound can cause accumulation of 8-oxoguanine in DNA in vitro and is a potent tool for the study of OGG1 biology.
Chemical properties
Technical inquiry about: 3D-BS167477 SU 0268
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