Product Information
Name:UNC 2881
Brand:Biosynth
Description:Inhibits Mer receptor tyrosine kinase (IC50 = 4.3 nM). Selective over Axl (84-fold) and Tyro3 (58-fold). UNC 2881 inhibits phosphorylation of Mer kinase in 697 B-ALL cells (IC50 = 22nM). Inhibits EGF-induced activation of a chimeric enzyme, composed of EGFR fused with Mer. Blocks collagen-mediated platelet aggregation, implying the potential of this compound for treating thrombosis.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:463.58 g/mol
Formula:C25H33N7O2
Purity:Min. 95%
Color/Form:Powder
Technical inquiry about: UNC 2881
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