Product Information
Name:VU 6010608
Synonyms:
- 3
- 4- Dimethoxy- N- [2- (1H- 1
- 2
- 4- triazol- 1- yl) - 5- (trifluoromethoxy) phenyl] -benzamide
Brand:Biosynth
Description:This compound is a novel negative allosteric modulator of glutamate metabotropic receptor mGlu7. It is highly selective for mGlu7 over other receptors of mGlu class with IC50 = 795 nM. Although VU 6010608 showed favourable brain penetration in rats, it has been proposed as an in vitro tool for electrophysiology studies. The mGlu7 is broadly distributed within the mammalian central nervous system and it plays a key role in neuronal function and synaptic plasticity.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:408.33 g/mol
Formula:C18H15F3N4O4
Purity:Min. 95%
Color/Form:Solid.
InChI:InChI=1S/C18H15F3N4O4/c1-27-15-6-3-11(7-16(15)28-2)17(26)24-13-8-12(29-18(19,20)21)4-5-14(13)25-10-22-9-23-25/h3-10H,1-2H3,(H,24,26)
InChI key:InChIKey=YCDOKDADFOBKIL-UHFFFAOYSA-N
SMILES:COc1ccc(C(=O)Nc2cc(OC(F)(F)F)ccc2-n2cncn2)cc1OC
Technical inquiry about: VU 6010608
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