HER-2 substrate peptide
Ref. 3D-CRB1000259
1mg
254.00€
5mg
588.00€
10mg
851.00€
25mg
1,093.00€
500µg
186.00€
Product Information
Name:HER-2 substrate peptide
Synonyms:
- H-GGMEDIYFEFMGGKKK-NH2HER2 substrate
Brand:Biosynth
Description:Human epidermal growth factor receptor 2 (HER-2)/epidermal growth factor receptor-2 (ErbB-2), is a key receptor linked to metastasis in tumours. The oncogenic ErbB-2 receptor has intrinsic receptor tyrosine kinase (RTK) activity. The receptor is activated by ligand binding which induces receptor dimerization. These RTK complexes can activate mitogen-activated protein kinase (MAPK) and phosphoinositol 3'-kinase (PI3K)/Akt pathways. This peptide has been identified as a substrate for HER-2/ErbB-2 as it is phosphorylated upon receptor activation and therefore acts as a marker for receptor activation in kinases assays.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1,836.14 g/mol
Purity:Min. 95%
Technical inquiry about: HER-2 substrate peptide
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