740 Y-P
Ref. 3D-CRB1000990
| 1mg | 501.00 € | ||
| 500µg | 406.00 € |
Product Information
- H-RQIKIWFQNRRMKWKKSDGG(pY)MDMS-OHRQIKIWFQNRRMKWKKSDGG-[pY]-MDMS-acidH-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys- Lys-Ser-Asp-Gly-Gly-[pTyr]-Met-Asp -Met-Ser-OH
Cell permeable peptide which is able to activate phosphoinositide 3- kinase, for which it binds with high affinity to the p85 subunit. 740 Y-P also has mitogenic activity as it is able to induce mitosis in muscle cells, and promotes cell survival in neurones. PI 3- kinase's are a family of enzymes involved in many cellular pathways including cell proliferation, growth, differentiation, survival, motility, and intracellular trafficking. PI 3 Kinases are therefore also involved in many cancers.
Chemical properties
Technical inquiry about: 3D-CRB1000990 740 Y-P
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