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epsilon - PKC Inhibitor
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epsilon - PKC Inhibitor

Ref. 3D-CRB1001138

1mg
298.00 €
500µg
218.00 €
Estimated delivery in United States, on Monday 23 Dec 2024

Product Information

Name:
epsilon - PKC Inhibitor
Synonyms:
  • H-EAVSLKPTC-OH
Description:

eV1-2 is a selective εPKC inhibitor peptide which interferes with protein-protein interactions between the ϵPKC isozyme and its anchoring protein (ϵRACK). ϵPKC and ϵRACK regulate the contraction rate of heart muscle cells and provide protection from ischemia induced cell death. ϵV1-2 is derived from the C2 domain of ϵPKC, a region important for protein-protein interactions and thus acts as a competitive inhibitor of these interactions. The C2 region is well conserved between species, but different enough from other PKC isozymes to allow for targeted inhibition (ϵV1-2 is 88% identical between sea slugs and rat ϵPKC, yet only 36% identical between rat ϵPKC and rat θ'PKC). This peptide contains a C-terminal cysteine residue for conjugation to a carrier protein.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
946.5 g/mol
Purity:
Min. 95%
Color/Form:
Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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