Autocamtide-3 Derived Inhibitory Peptide(AC3 - I)
Ref. 3D-CRB1001140
| 1mg | 298.00 € | ||
| 500µg | 218.00 € |
Product Information
- Myr-KKALHRQEAVDAL-OH
Autocamtide-3-related inhibitory peptide is a calmodulin-dependent protein kinase II (CaMKII) inhibitor. AC3-I is derived from Autocamtide-3, a substrate for CaMKII, with the Thr-9 phosphorylation site substituted with Ala.CAMK represents a class of Ca2+/calmodulin-dependent protein kinase enzymes. CAMKs are activated by increases in the concentration of intracellular calcium ions (Ca2+) and transfers phosphates from ATP to defined serine or threonine residues in other proteins. Activated CAMK is involved in the phosphorylation of transcription factors and therefore, in the regulation of expression of responding genes.
Chemical properties
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