Bazedoxifene 5-β-D-glucuronide

CAS: 328933-56-8

Ref. 3D-DNA93356

Product Information

• Name: Bazedoxifene 5-β-D-glucuronide
• Brand: Biosynth
• Description: Bazedoxifene 5-β-D-glucuronide is an analog of bazedoxifene, a selective estrogen receptor modulator used in the treatment of osteoporosis. This compound has shown promising anticancer properties and has been studied extensively in Chinese hamster ovary cells. Bazedoxifene 5-β-D-glucuronide has been found to induce apoptosis in cancer cells and inhibit the activity of kinases involved in tumor growth. It is a potent inhibitor of several human protein kinases, including cyclin-dependent kinase 2 (CDK2) and glycogen synthase kinase 3 beta (GSK3β), which are important targets for medicinal chemists developing kinase inhibitors. This compound is excreted primarily in urine and may have potential as a therapeutic agent for various types of cancer.

Chemical properties

• Molecular weight: 646.7 g/mol
• Formula: C₃₆H₄₂N₂O₉
• Purity: Min. 95%
• Color/Form: Powder