Caspase substrate
CAS: 219138-02-0
Ref. 3D-EC58694
| 5mg | 348.00 € | ||
| 10mg | 474.00 € | ||
| 25mg | 1,049.00 € | ||
| 50mg | 1,902.00 € | ||
| 100mg | 3,499.00 € |
Product Information
- Z-Ile-Glu-Thr-Asp-AFCZ-IETD-AFC
- Z-Ietd-Afc
Caspase substrates are a class of pharmacological agents that regulate apoptosis. Caspases are proteases that cleave specific proteins in the cell, leading to apoptosis. Pro-apoptotic proteins activate caspases, while anti-apoptotic proteins inhibit them. Caspase substrates can be either pro-caspase or anti-caspase, depending on the desired effect. They may also be used to regulate caspases without affecting their activity. The caspase substrate is cleaved by caspases and releases a polypeptide fragment that triggers apoptosis in some cells, but not others. For example, the Hl-60 cell line is resistant to the pro-apoptotic effects of the substrate because it contains an anti-apoptotic protein called Bcl-2. In contrast, myocardial cells contain pro-apoptotic proteins and are sensitive to the pro-apoptotic effects of the substrate. In
Chemical properties
Technical inquiry about: 3D-EC58694 Caspase substrate
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
