Product Information
GW806742X is a potent and selective inhibitor of caspase-independent cell death. It provides a new therapeutic option for the treatment of inflammatory diseases, bowel disease, and leukemia. GW806742X has been shown to inhibit the activation of aurora kinases, which are key regulators in the inflammatory response. The compound also blocks necroptosis induced by complement-dependent cytotoxicity or cellular inflammatory stimuli. GW806742X inhibits the release of proinflammatory cytokines and chemokines such as IL-1β and TNFα, which may be due to its ability to block NF-κB activity.
Chemical properties
Technical inquiry about: 3D-EYA51563 GW806742X
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