Estimated delivery in United States, on Tuesday 28 May 2024
Product Information
Name:
AG 120
Synonyms:
- Ivosidenib
CAS:
Description:
Inhibits isocitrate dehydrogenase 1 (IDH-1) harbouring a gain of function mutation at R132, which causes impaired cellular differentiation via epigenetic modulation. By inhibiting mutant IDH1, synthesis of oncometabolite 2-hydroxyglutarate is reduced. This compound therefore has therapeutic potential in solid and haematological malignancies, such as acute myeloid leukemia (AML).
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
582.96 g/mol
Formula:
C28H22ClF3N6O3
Purity:
Min. 95%
Color/Form:
White To Off-White Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: 3D-FA145491 AG 120
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