(2R)-Arimoclomol maleate
CAS: 289893-26-1
Ref. 3D-FA159627
| 5mg | 136.00 € | ||
| 10mg | 195.00 € | ||
| 25mg | 356.00 € | ||
| 50mg | 542.00 € | ||
| 100mg | 863.00 € |
Product Information
- N-{[(2R)-2-Hydroxy-3-piperidin-1-ylpropyl]oxy}pyridine-3-carboximidoyl Chloride 1-Oxide maleic acid
(2R)-Arimoclomol maleate is a prodrug that is metabolized to the active drug, dimebon. It has been shown to inhibit the interaction of Hsp70 with its substrate, which in turn inhibits the activity of Hsp70. This inhibition prevents the accumulation of misfolded proteins and thus prevents cytotoxicity. (2R)-Arimoclomol maleate is also a linker for enzymatic activity and interacts with residues in proteins that are involved in signal transduction. It can modulate the onset of action and duration of effect by altering the level of active drug present.
Chemical properties
Technical inquiry about: 3D-FA159627 (2R)-Arimoclomol maleate
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