Acetohexamide

CAS: 968-81-0

Ref. 3D-FA16951

Product Information

• Name: Acetohexamide
• Synonyms: 4-Acetyl-N-[(cyclohexylamino)carbonyl]benzenesulfonamideAcetohexamidDimelin, 1-(4-Acetylbenzenesulfonyl)-3-Cyclohexylurea, 1-(4-Acetylphenyl)sulfonyl-3-cyclohexylurea, 1-(p-Acetylbenzenesulfonyl)-3-cyclohexylurea, 1-[(p-Acetylphenyl)sulfonyl]-3-cyclohexylurea, 4-Acetyl-N-[(cyclohexylamino)carbonyl]benzenesulfonamide, 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide, Acetohexamid, Acetohexamida, Benzenesulfonamide, 4-acetyl-N-[(cyclohexylamino)carbonyl]-, Dimelin, Dimelin (antidiabetic), Dimelor, Dymelor, Gamadiabet, Hypoglicil, Metaglucina, Minoral, N-(p-Acetylphenylsulfonyl)-N'-cyclohexylurea, Ordimel, Tsiklamid, U 14812, Urea, 1-[(p-acetylphenyl)sulfonyl]-3-cyclohexyl-

Description

Acetohexamide is a hypoglycemic drug that binds to the sulfonylurea receptor on pancreatic beta-cells and stimulates insulin release. It has been shown to have an oral hypoglycemic effect in humans, as well as in rats. Acetohexamide has been shown to inhibit the action of nonsteroidal anti-inflammatory drugs, such as indomethacin, through competitive inhibition. Acetohexamide also inhibits the enzyme activity of estradiol benzoate and acetohexamide hydrolase. This drug is not active against bacteria or fungi, but has been shown to be effective against some viruses. Acetohexamide is absorbed by the gastrointestinal tract and excreted unchanged in urine and feces. The drug does not bind to proteins and does not cross the blood-brain barrier.

• Brand: Biosynth

Chemical properties

• Molecular weight: 324.4 g/mol
• Formula: C₁₅H₂₀N₂O₄S
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C15H20N2O4S/c1-11(18)12-7-9-14(10-8-12)22(20,21)17-15(19)16-13-5-3-2-4-6-13/h7-10,13H,2-6H2,1H3,(H2,16,17,19)
• InChI key: InChIKey=VGZSUPCWNCWDAN-UHFFFAOYSA-N
• SMILES: CC(=O)c1ccc(S(=O)(=O)NC(=O)NC2CCCCC2)cc1