H-9 hydrochloride

CAS: 116970-50-4

Ref. 3D-FA17738

Product Information

• Name: H-9 hydrochloride
• Synonyms: N-(2-Aminoethyl)-5-isoquinolinesulfonamide hydrochlorideH 9
• Brand: Biosynth
• Description: H-9 hydrochloride is a selective protein kinase inhibitor, which is synthetically derived. It primarily inhibits cyclic nucleotide-dependent protein kinases, including protein kinase A (PKA) and protein kinase G (PKG), along with myosin light chain kinase (MLCK). The mode of action involves competitive inhibition at the ATP binding site of these kinases, thereby impacting phosphorylation pathways crucial for multiple physiological functions. The selective inhibition by H-9 hydrochloride allows for detailed exploration of kinase-mediated signaling pathways in cellular biology. Moreover, it is extensively utilized in studies involving cell motility, smooth muscle contraction, and signal transduction. The relevance of H-9 hydrochloride in academic research lies in its ability to provide insights into kinase activity modulation and its ensuing effects on cellular dynamics. This compound serves as an invaluable tool for scientists aiming to elucidate the complex role of protein kinases in health and disease, enabling the development of innovative therapeutic strategies.

Chemical properties

• Molecular weight: 287.77 g/mol
• Formula: C₁₁H₁₄ClN₃O₂S
• Purity: Min. 95%
• Color/Form: White To Off-White Solid