Product Information
Name:Aminopterin
Synonyms:
- N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid4-Aminofolic acid
- 4-aminopteroyl-L-glutamic acid
- 4-amino-PG ANSC 739
Brand:Biosynth
Description:Aminopterin is an antineoplastic agent and antifolate, which is a synthetic derivative of pteroylglutamic acid. It functions as a chemotherapeutic agent by inhibiting dihydrofolate reductase, an enzyme crucial in the folic acid pathway, thereby preventing the conversion of dihydrofolate to tetrahydrofolate. This disruption leads to impaired synthesis of purine nucleotides and thymidylate, which are essential for DNA synthesis and cell division.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:440.41 g/mol
Formula:C19H20N8O5
Purity:Min. 97 Area-%
Color/Form:Slightly Yellow Powder
Technical inquiry about: Aminopterin
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