Alendronic acid

CAS: 66376-36-1

Ref. 3D-FA38407

Product Information

• Name: Alendronic acid
• Synonyms: (4-Amino-1-hydroxy-1-phosphonobutyl) phosphonic acid, (4-Amino-1-hydroxybutylidene)bisphosphonic acid, 4-Amino-1-hydroxybutane-1,1-bisphosphonic acid, 4-Amino-1-hydroxybutane-1,1-diphosphonate, 4-Amino-1-hydroxybutane-1,1-diphosphonic acid, 4-Amino-1-hydroxybutane-1,1-diyldiphosphonic acid, 4-Amino-1-hydroxybutylidene-1,1-bis(phosphonic acid), A-Hydroxy-D-Aminobutylidenediphosphonic Acid, Abdp, Bph 1, Marvil, P,P′-(4-Amino-1-hydroxybutylidene)bis[phosphonic acid], Phosphonic acid, (4-amino-1-hydroxybutylidene)bis-, Phosphonic acid, P,P′-(4-amino-1-hydroxybutylidene)bis-

Description

Alendronic acid is a drug that is used for the treatment of postmenopausal osteoporosis. It belongs to the class of drugs called bisphosphonates and inhibits bone resorption by inhibiting the activity of osteoclasts, which are cells that break down bone tissue. Alendronic acid has been shown to decrease bone loss in women who are treated with this drug. A two-way crossover study was conducted on postmenopausal women to evaluate the efficacy of alendronate sodium (alendronic acid) in reducing the risk of fracture. Results showed that alendronate significantly increased bone mineral density and decreased fracture rates. An analytical method was developed to determine the concentration of alendronate in biological samples using electrochemical impedance spectroscopy.

• Brand: Biosynth

Chemical properties

• Molecular weight: 249.1 g/mol
• Formula: C₄H₁₃NO₇P₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C4H13NO7P2/c5-3-1-2-4(6,13(7,8)9)14(10,11)12/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12)
• InChI key: InChIKey=OGSPWJRAVKPPFI-UHFFFAOYSA-N
• SMILES: NCCCC(O)(P(=O)(O)O)P(=O)(O)O