Product Information
- (2S)-2-Amino-2-[(1S,2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl) propanoic acid
- (1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]cyclopropanecarboxylic acid
- (αS)-α-Amino-α-[(1S,2S)-2-carboxycyclopropyl]-9H-xanthene-9-propanoic acid
- 9H-Xanthene-9-propanoic acid, α-amino-α-(2-carboxycyclopropyl)-, [1S-[1α(R*),2β]]-
- 9H-Xanthene-9-propanoic acid, α-amino-α-[(1S,2S)-2-carboxycyclopropyl]-, (αS)-
- Ly-341495
A highly potent antagonist of group II metabotropic glutamate receptors (IC50 values = 21 nM and 14 nM at human mGluR2 and mGluR3 respectively). LY 341495 also inhibits group I and III mGluRs with lower potencies (IC50 values = 0.17, 7.8 and 8.2 µM at mGluR8, mGluR1a and mGluR5a respectively). There has been contradicting findings on the antidepressant and anxiolytic activities of this compound. Enhanced cognitive function and locomotor activity have also been described for LY 341495.
Chemical properties
Technical inquiry about: 3D-FA65069 LY 341495
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