Product Information
- β-D-Glucopyranoside, 1,4a,5,6,7,7a-hexahydro-5,7-dihydroxy-7-methylcyclopenta[c]pyran-1-yl, [1S-(1α,4aα,5α,7α,7aα)]-
- β-D-Glucopyranoside, (1S,4aR,5R,7S,7aS)-1,4a,5,6,7,7a-hexahydro-5,7-dihydroxy-7-methylcyclopenta[c]pyran-1-yl
- (1S,4aR,5R,7S,7aS)-1,4a,5,6,7,7a-Hexahydro-5,7-dihydroxy-7-methylcyclopenta[c]pyran-1-yl β-D-glucopyranoside
Ajugol is a cox-2 inhibitor that has been proven to be effective in inhibiting the production of inflammatory prostaglandins. Ajugol is a natural compound found in the seeds of Ajuga plants, and it inhibits COX-2 enzymes by binding to the active site of these enzymes, preventing them from converting arachidonic acid into prostaglandin H2 (PGH2). Ajugol has been shown to inhibit the growth of HLA-60 cells and induce apoptosis by increasing mitochondrial membrane potential. This drug also reduces the production of inflammatory cytokines such as TNF-α and IL-1β. The pharmacokinetic properties and analytical methods for this drug are not well understood. Ajugol has also been shown to be effective in treating autoimmune diseases such as type 1 diabetes mellitus.
Chemical properties
Technical inquiry about: 3D-FA74117 Ajugol
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