Product Information
Name:TDZD 8
Synonyms:
- GSK-3b inhibitor I4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
Brand:Biosynth
Description:TDZD 8 is a selective, non-ATP competitive inhibitor of the glycogen synthase kinase GSK3β. TDZD 8 inhibits GSK3β with IC50 of 2 μM and was reported to not significantly affect Cdk-1/cyclin B, casein kinase CK-II, protein kinase A and C (PKA, PKC) activities. TDZD 8 was also identified as an inhibitor of the main protease in coronaviruses. In an in vitro study, TDZD 8 was characterised as an aggregate-based inhibitor as the presence of Triton-X decreased the inhibitory potency to Mpro protease of the SARS-CoV-2 virus (IC50 without Triton-X: 2.15 μM).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:222.26 g/mol
Formula:C10H10N2O2S
Purity:Min. 98 Area-%
Color/Form:Powder
InChI:InChI=1S/C10H10N2O2S/c1-11-9(13)12(10(14)15-11)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3
InChI key:InChIKey=JDSJDASOXWCHPN-UHFFFAOYSA-N
SMILES:Cn1sc(=O)n(Cc2ccccc2)c1=O
Technical inquiry about: TDZD 8
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.