(15R)-Bimatoprost

CAS: 1163135-92-9

Ref. 3D-FB18597

Product Information

• Name: (15R)-Bimatoprost
• Synonyms: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-ethyl-5-heptenamide
• Brand: Biosynth
• Description: (15R)-Bimatoprost is a prostaglandin analogue that is used to treat glaucoma. It is an esterification of the corresponding acid with 15-deoxy-Δ12,14-prostaglandin J2 (PGD2), which is a metabolite of prostaglandin F2α (PGF2α). The esterification reaction requires an alcohol, such as methanol or ethanol, and a carboxylic acid chloride to react with the PGD2. This synthesis can be accomplished using a convergent approach that involves one or more reagents, including phenylsulfone and olefination. Other analogues of bimatoprost include travoprost and latanoprost.

Chemical properties

• Molecular weight: 415.57 g/mol
• Formula: C₂₅H₃₇NO₄
• Purity: Min. 95%
• Color/Form: Powder