6-Bromoisatin

CAS: 6326-79-0

Ref. 3D-FB19026

Product Information

• Name: 6-Bromoisatin
• Synonyms: 6-Bromo-1H-indole-2,3-dione6-Bromoindole-2,3-dione6-Bromo isatinic anhydride, 6-Bromoindole-2,3-dione, 6-bromo-1H-indole-2,3-dione, Indole-2,3-dione,6-bromo- (8CI), Nsc 30748, 1H-Indole-2,3-dione,6-bromo-, 6-Bromo-2,3-Indolinedione

Description

6-Bromoisatin is an antimicrobial agent that belongs to the group of ethylene diamines. It has been shown to be a potent inhibitor of cancer cell viability in vivo and can be used as a potential chemotherapy agent. 6-Bromoisatin is active against human pathogens, such as Staphylococcus aureus and Streptococcus pyogenes. This compound has also been shown to inhibit the growth of LPS-stimulated RAW264.7 macrophages, which are used in vitro for studying innate immunity. The mechanism of action involves inhibition of cyclic AMP production, which leads to cell death in cancer cells. 6-Bromoisatin also inhibits the proliferation and viability of granulosa cells and carcinoma cells, with IC50 values in the range of 0.5 - 2 µM.END>>

• Brand: Biosynth

Chemical properties

• Molecular weight: 226.03 g/mol
• Formula: C₈H₄BrNO₂
• Purity: Min. 95%
• Color/Form: Yellow Powder
• InChI: InChI=1S/C8H4BrNO2/c9-4-1-2-5-6(3-4)10-8(12)7(5)11/h1-3H,(H,10,11,12)
• InChI key: InChIKey=HVPQMLZLINVIHW-UHFFFAOYSA-N
• SMILES: O=C1Nc2cc(Br)ccc2C1=O