Product Information
Name:SB 431542
Synonyms:
- 4-(4-Benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide
Brand:Biosynth
Description:Inhibitor of activin receptor-like kinases (ALK4, ALK5 and ALK7), members of TGFβ type I receptor family. Blocks activin- and TGFβ-mediated signaling and phosphorylation of Smad2 downstream. Suppresses tumor-promoting and tumor-suppressing effects of TGFβ. Promotes differentiation of human embryonic stem cells (hESCs), whilst sustaining mouse ESCs in the undifferentiated state.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:384.4 g/mol
Formula:C22H16N4O3
Purity:Min. 98 Area-%
Color/Form:Powder
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