2-Bromo-3-fluorobenzoic acid

CAS: 132715-69-6

Ref. 3D-FB38482

Product Information

• Name: 2-Bromo-3-fluorobenzoic acid
• Synonyms: 3-Fluoro-2-bromobenzoic acid

Description

2-Bromo-3-fluorobenzoic acid is a chemical compound that can be synthesized by the reduction of nitrobenzene with ammonium chloride. This reaction is regioselective, giving predominantly 2-bromo-3-fluorobenzoic acid. The reaction proceeds via a nucleophilic substitution mechanism and the product is formed in high yield. A second route for the synthesis of 2-bromo-3-fluorobenzoic acid involves the deamination of trifluorotoluene to produce hypophosphorous acid, which reacts with sulfuric acid to give 2-bromo-3-fluorobenzoic acid. The bromine atom in this molecule has a high nucleophilicity and reacts readily with electrophiles such as ammonia and amines.

• Brand: Biosynth

Chemical properties

• Molecular weight: 219.01 g/mol
• Formula: C₇H₄BrFO₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C7H4BrFO2/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3H,(H,10,11)
• InChI key: InChIKey=KQRCBMPPEPNNDS-UHFFFAOYSA-N
• SMILES: O=C(O)c1cccc(F)c1Br