(E,E)-Bisdemethoxycurcumin

CAS: 33171-05-0

Ref. 3D-FB64958

Product Information

• Name: (E,E)-Bisdemethoxycurcumin
• Synonyms: (1E,6E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dioneCurcumin III, (1E,6E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione, (1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione, (1E,6E)-Bis(demethoxy)curcumin, 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)-, 1,6-Heptadiene-3,5-dione, 1,7-bis(p-hydroxyphenyl)-, (E,E)-, 1,7-Bis(4-Hydroxyphenyl)Hepta-1,6-Diene-3,5-Dione, Bisdesmethoxycurcumin, Curcumin III, Didemethoxycurcumin
• CAS: 33171-05-0

Description

Bisdemethoxycurcumin is a pro-apoptotic protein that has been shown to inhibit the growth of cancer cells by inducing apoptosis. It has been shown to stimulate the release of p-hydroxybenzoic acid from the cells and activate signal pathways such as growth factor-β1 and toll-like receptor, leading to apoptosis. Bisdemethoxycurcumin also inhibits the production of inflammatory cytokines and chemokines in human monocytes, which may be beneficial for bowel disease. This compound has been shown to have antioxidant effects and inhibit the proliferation of 3T3-L1 preadipocytes in a model system. Bisdemethoxycurcumin is produced by heating curcumin with an organic solvent, such as ethanol or acetone.
Bisdemethoxycurcumin is used in analytical chemistry as a reagent for determining the concentration of uric acid in urine samples.

• Brand: Biosynth

Chemical properties

• Molecular weight: 308.33 g/mol
• Formula: C₁₉H₁₆O₄
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C19H16O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-12,20-21H,13H2/b11-5+,12-6+
• InChI key: InChIKey=PREBVFJICNPEKM-YDWXAUTNSA-N
• SMILES: O=C(/C=C/c1ccc(O)cc1)CC(=O)/C=C/c1ccc(O)cc1