CAS 33171-05-0
:Bisdemethoxycurcumin
Description:
Bisdemethoxycurcumin is a synthetic derivative of curcumin, which is the active compound found in turmeric. It is characterized by its unique chemical structure, which lacks two methoxy groups present in curcumin, resulting in distinct physical and chemical properties. This compound typically exhibits a yellow to orange color and is known for its potential biological activities, including anti-inflammatory, antioxidant, and anticancer properties. Bisdemethoxycurcumin is soluble in organic solvents but has limited solubility in water, which can affect its bioavailability. Its mechanism of action is thought to involve the modulation of various signaling pathways, making it a subject of interest in pharmacological research. Additionally, studies have indicated that it may enhance the efficacy of certain chemotherapeutic agents. As with many compounds derived from natural sources, further research is necessary to fully understand its therapeutic potential and safety profile.
Formula:C19H16O4
InChI:InChI=1S/C19H16O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-12,20-21H,13H2/b11-5+,12-6+
InChI key:InChIKey=PREBVFJICNPEKM-YDWXAUTNSA-N
SMILES:C(=C/C(CC(/C=C/C1=CC=C(O)C=C1)=O)=O)\C2=CC=C(O)C=C2
Synonyms:- (1E,6E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
- (1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
- (1E,6E)-Bis(demethoxy)curcumin
- 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxyphenyl)-, (1E,6E)-
- 1,6-Heptadiene-3,5-dione, 1,7-bis(p-hydroxyphenyl)-, (E,E)-
- 1,7-Bis(4-Hydroxyphenyl)Hepta-1,6-Diene-3,5-Dione
- Bisdesmethoxycurcumin
- Curcumin III
- Didemethoxycurcumin
- Bisdemethoxycurcumin
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Bisdemethoxycurcumin
CAS:Formula:C19H16O4Purity:>95.0%(HPLC)(T)Color and Shape:Light yellow to Yellow to Orange powder to crystalMolecular weight:308.33Bisdesmethoxycurcumin
CAS:Ketone-phenols and ketones with other oxygen functionFormula:C19H16O4Color and Shape:Yellow Orange PowderMolecular weight:308.10486(1E,6E)-Bis(demethoxy)curcumin
CAS:(1E,6E)-Bis(demethoxy)curcuminFormula:C19H16O4Purity:≥95%Molecular weight:308.33Bisdemethoxycurcumin
CAS:Bisdemethoxycurcumin can regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism, also suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways.Formula:C19H16O4Purity:95%~99%Color and Shape:Yellow powderMolecular weight:308.333(1E,6E)-Bis(demethoxy)curcumin (Standard)
CAS:(1E,6E)-Bis(demethoxy)curcumin (Standard) is a reference standard for research and analysis in studies involving (1E,6E)-Bis(demethoxy)curcumin. (1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.Formula:C19H16O4Molecular weight:308.3279Bisdemethoxycurcumin
CAS:Bisdemethoxycurcumin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C19H16O4Purity:(HPLC) ≥98%Color and Shape:PowderMolecular weight:308.33(E,E)-Bisdemethoxycurcumin
CAS:Controlled ProductStability Light Sensitive
Applications Bisdemethoxycurcumin is one of the three major forms of curcuminoids found in the rhizomes of turmeric. Bisdemethoxycurcumin displays antioxidant, anti-inflammatory as well as chemotherapeutic activity. Bisdemethoxycurcumin acts as an inhibitor of human pancreatic α-amylase, a target for type-2 diabetes .
References Ponnusamy, S. et al.: Food Chem., 135, 2638 (2012); Hung, C.-M. et al.: J. Agric. Food. Chem., 60, 8427 (2012); Jayaprakasha, G.K. et al.: Food Chem., 98, 720 (2006);Formula:C19H16O4Color and Shape:NeatMolecular weight:308.33(E,E)-Bisdemethoxycurcumin-d8
CAS:Controlled ProductApplications Labelled analogue of Bisdemethoxycurcumin, one of the three major forms of curcuminoids found in the rhizomes of turmeric. Bisdemethoxycurcumin displays antioxidant, anti-inflammatory as well as chemotherapeutic activity. Bisdemethoxycurcumin acts as an inhibitor of human pancreatic α-amylase, a target for type-2 diabetes .
References Ponnusamy, S. et al.: Food Chem., 135, 2638 (2012); Hung, C.-M. et al.: J. Agric. Food. Chem., 60, 8427 (2012); Jayaprakasha, G.K. et al.: Food Chem., 98, 720 (2006);Formula:C19H8D8O4Color and Shape:NeatMolecular weight:316.38(1E,6E)-Bis(demethoxy)curcumin
CAS:(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.Formula:C19H16O4Purity:97.45% - 98.39%Color and Shape:Orange SolidMolecular weight:308.3279(E,E)-Bisdemethoxycurcumin
CAS:(1E,6E)-1,7-Bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dioneFormula:C19H16O4Purity:98%Molecular weight:308.33Bisdemethoxycurcumin
CAS:Ketone phenolFormula:C19H16O4Purity:≥ 95.0 % (HPLC)Color and Shape:PowderMolecular weight:308.33(E,E)-Bisdemethoxycurcumin - Bio-X ™
CAS:Bisdemethoxycurcumin is a natural product that has been shown to inhibit the growth of cancer cells by inducing apoptosis. Bisdemethoxycurcumin also inhibits the production of inflammatory cytokines and chemokines in human monocytes, which may be beneficial for bowel disease. This compound has been shown to have antioxidant effects and anti-inflammatory properties.Formula:C19H16O4Purity:Min. 95%Color and Shape:PowderMolecular weight:308.33 g/mol(E,E)-Bisdemethoxycurcumin
CAS:(E,E)-Bisdemethoxycurcumin is a natural curcuminoid, which is a type of polyphenolic compound. This compound is sourced primarily from the rhizomes of the turmeric plant, Curcuma longa. Its molecular structure is characterized by the absence of methoxy groups, distinguishing it from other curcuminoids.Formula:C19H16O4Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:308.33 g/mol
