Estimated delivery in United States, on Tuesday 10 Dec 2024
Product Information
Name:
BIX 02188
Description:
A selective inhibitor of MEK5 protein kinase with an IC50 value of 4.3 nM. Blocks transcriptional activation of myocyte-specific enhancer factor 2C (MEF2C). Inhibits phosphorylation of ERK5 protein kinase and thereby reverses inhibition of TNF signaling induced by fluid shear stress in endothelial cells. Induces apoptosis in FLT3-ITD cells.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
412.18993
Formula:
C25H24N4O2
Purity:
Min. 95%
InChI:
InChI=1S/C25H24N4O2/c1-29(2)15-16-7-6-10-19(13-16)27-23(17-8-4-3-5-9-17)22-20-12-11-18(24(26)30)14-21(20)28-25(22)31/h3-14,28,31H,15H2,1-2H3,(H2,26,30)/b27-23+
InChI key:
InChIKey=WGPXKFOFEXJMBD-SLEBQGDGSA-N
SMILES:
CN(C)Cc1cccc(/N=C(\c2ccccc2)c2c(O)[nH]c3cc(C(N)=O)ccc23)c1
MDL:
Melting point:
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HS code:
Technical inquiry about: 3D-FB64959 BIX 02188
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