2'-Bromo-4'-fluoroacetanilide

CAS: 1009-22-9

Ref. 3D-FB71093

Product Information

• Name: 2'-Bromo-4'-fluoroacetanilide
• Brand: Biosynth
• Description: 2'-Bromo-4'-fluoroacetanilide is a synthetic derivative of acetanilide that is used in the treatment of diabetes mellitus. It has been shown to have antidiabetic properties as well as to inhibit the formation of nitrosamines, which are carcinogenic compounds. The synthesis of 2'-bromo-4'-fluoroacetanilide involves the addition of bromine and sodium hydrogen to acetylated acetanilide. This reaction occurs in a reaction vessel at an elevated temperature, with the solvent being an organic solvent. The final product is isolated by distillation and purified by recrystallization or column chromatography. Molecular docking analysis has shown that 2'-bromo-4'-fluoroacetanilide binds to ATP synthase, which is involved in gluconeogenesis and glycolysis, leading to its ability to inhibit glucose production in cells.

Chemical properties

• Molecular weight: 232.05 g/mol
• Formula: C₈H₇BrFNO
• Purity: Min. 95%
• InChI: InChI=1S/C8H7BrFNO/c1-5(12)11-8-3-2-6(10)4-7(8)9/h2-4H,1H3,(H,11,12)
• InChI key: InChIKey=JAVSBNOXENOHEI-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1ccc(F)cc1Br