Product Information
- 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-pyrrol-2-yl-
- 2H-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-
- 7-Chloro-1,3-dihydro-5-(1H-pyrrol-2-yl)-2H-1,4-benzodiazepin-2-one
- NSC 66020
Ro 5-3335 is a synthetic substance that inhibits the production of tumor necrosis factor-α (TNF-α), which is a cytokine that has been shown to induce choroidal neovascularization. Ro 5-3335 has synergistic effects with other drugs such as fluorescein, which can be used to study the progression of choroidal neovascularization in vivo. The anti-inflammatory effect of Ro 5-3335 may be due to its ability to inhibit the synthesis of TNF-α by binding to TNF-α response elements on DNA. This drug also induces cell death by inhibiting growth factor or messenger RNA production or by acting on specific cells such as toll-like receptor 2 and 4.
Chemical properties
Technical inquiry about: 3D-FBA19530 Ro 5-3335
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