Canagliflozin hemihydrate

CAS: 928672-86-0

Ref. 3D-FC103621

Product Information

• Name: Canagliflozin hemihydrate
• Brand: Biosynth
• Description: Canagliflozin is an oral diabetes drug that belongs to the class of sodium-glucose cotransporter 2 (SGLT2) inhibitors. It works by blocking reabsorption of glucose in the kidney, thereby lowering blood sugar levels. Canagliflozin has been shown to be a potent inhibitor of insulin resistance and has been used clinically in combination with metformin hydrochloride. The chemical stability of canagliflozin is dependent on its particle size, which can range from 10 micrometres to 100 micrometres. A number of analytical methods have been developed for canagliflozin, including high performance liquid chromatography with ultraviolet detection, gas chromatography with mass spectrometry detection, and dihedral angle analysis. Canagliflozin is an example of a polymorphic compound: it exists as two enantiomers due to chiral symmetry.

Chemical properties

• Molecular weight: 907.05 g/mol
• Formula: (C₂₄H₂₅FO₅S)₂•H₂O
• Purity: Min. 95%
• Color/Form: Powder