CCT 241533 hydrochloride
CAS: 1431697-96-9
Ref. 3D-FC104262
| 1mg | 225.00 € | ||
| 2mg | 349.00 € | ||
| 5mg | 647.00 € | ||
| 10mg | 863.00 € | ||
| 25mg | 1,594.00 € |
Estimated delivery in United States, on Friday 17 Jan 2025
Product Information
Name:
CCT 241533 hydrochloride
Synonyms:
- 3-Pyrrolidinemethanol, 4-[[2-(5-fluoro-2-hydroxyphenyl)-6,7-dimethoxy-4-quinazolinyl]amino]-α,α-dimethyl-, hydrochloride (1:1), (3R,4S)-rel-
Description:
Potent and specific inhibitor of checkpoint kinase CHK2 with IC50 of 3 nM. CCT 241533 binds to the ATP pocket of CHK2 and shows minimal cross-reactivity against related kinases. CCT 241533 blocked the activity of CHK2 and impaired DNA repair in response to DNA damage in human tumoral cell lines. The compound did not potentiate genotoxicity of several genotoxic compounds but it did potentiate the cytotoxicity of a PARP inhibitor olaparib.
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
478.94 g/mol
Formula:
C23H27FN4O4•HCl
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
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