CCT 241533 hydrochloride
CAS:
Ref. 3D-FC104262
1mg
211.00€
2mg
349.00€
5mg
607.00€
10mg
806.00€
25mg
1,491.00€
Product Information
Name:CCT 241533 hydrochloride
Brand:Biosynth
Description:Potent and specific inhibitor of checkpoint kinase CHK2 with IC50 of 3 nM. CCT 241533 binds to the ATP pocket of CHK2 and shows minimal cross-reactivity against related kinases. CCT 241533 blocked the activity of CHK2 and impaired DNA repair in response to DNA damage in human tumoral cell lines. The compound did not potentiate genotoxicity of several genotoxic compounds but it did potentiate the cytotoxicity of a PARP inhibitor olaparib.
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Chemical properties
Molecular weight:478.94 g/mol
Formula:C23H27FN4O4•HCl
Purity:Min. 95%
Technical inquiry about: CCT 241533 hydrochloride
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