Clothiapine

CAS: 2058-52-8

Ref. 3D-FC178187

Product Information

• Name: Clothiapine
• Synonyms: 2-Chloro-11-(4-Methylpiperazin-1-Yl)Dibenzo[B,F][1,4]Thiazepine, 2-Chloro-11-(4-methyl-1-piperazinyl)dibenzo(b,f)(1,4)thiazepine, 2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)thiazepine, Brn 0568276, Clothiapin, Clothiapine [USAN:BAN], Clotiapina, Clotiapina [INN-Spanish], Clotiapinum, Clotiapinum [INN-Latin], Deliton, Dibenzo(b,f)(1,4)thiazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-, Dibenzothiazepine, Entumin, Entumine, Etomine, Etumine, Hf 2159, Lw 2159, S-805C, Unii-Z05Hcy0X1T, W 130

Description

Clothiapine is a drug that belongs to the class of benzodiazepines. It is used in the pharmacological treatment of schizophrenia and other psychotic disorders, especially those associated with hallucinations. Clothiapine acts on the central nervous system by enhancing the effects of dopamine, which may be due to its ability to act as a partial agonist at D2 receptors. This drug has been shown to have anticonvulsant properties and can also be used for treating anxiety disorders, such as panic disorder and posttraumatic stress disorder. Clothiapine has been shown to have no effect on locomotor activity or receptor activity in mice.

• Brand: Biosynth

Chemical properties

• Molecular weight: 343.091
• Formula: C₁₈H₁₈ClN₃S
• Purity: Min. 95%
• InChI: InChI=1S/C18H18ClN3S/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3
• InChI key: InChIKey=KAAZGXDPUNNEFN-UHFFFAOYSA-N
• SMILES: CN1CCN(C2=Nc3ccccc3Sc3ccc(Cl)cc32)CC1