Cefmenoxime hydrochloride

CAS: 75738-58-8

Ref. 3D-FC19858

Product Information

• Name: Cefmenoxime hydrochloride
• Synonyms: (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicy clo[4.2.0]oct-2-ene-2-carboxylic acid hemihydrochlorideAbbott 50192Bestcall, (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride (2:1), 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), [6R-[6α,7β(Z)]]-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), (6R,7R)-, 7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hemihydrochloride, 7beta-[2-(2-Aminothiazol-4-yl)-(Z)-2-(methoxyiminoacetamido)]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid hemihydrochloride, Abbott 50192, Bestcall, Bestron, Cefmax, Cefmenoxime Hcl, Cefmenoxime hemihydrochloride, Cefmenoxime.1.5 HCl, Cemix, SCE-1365(free acid), Tacef

Description

Cefmenoxime is a third-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis. It binds to the penicillin-binding protein and blocks the cross-linkages between peptidoglycan strands in the bacterial cell wall. This prevents the formation of an enzyme-substrate complex, which is required for bacterial cell wall biosynthesis, leading to inhibition of protein synthesis and cell division. Cefmenoxime has been shown to be active against a wide range of bacteria including Enterobacteriaceae, Pseudomonas aeruginosa, and methicillin-resistant Staphylococcus aureus (MRSA). The drug is not active against Gram-negative aerobic bacilli or anaerobic bacteria. Cefmenoxime is rapidly absorbed from the gastrointestinal tract and has a high bioavailability. It has been detected in maternal blood and human serum at concentrations similar to those found in plasma. The drug is excreted by

• Brand: Biosynth

Chemical properties

• Molecular weight: 529.79 g/mol
• Formula: C₁₆H₁₇N₉O₅S₃HCl
• Purity: Min. 95%
• Color/Form: White Powder