Cevimeline hydrochloride

CAS: 107220-28-0

Ref. 3D-FC19916

Product Information

• Name: Cevimeline hydrochloride
• Synonyms: (+/-)-cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine hydrochlorideAF-102BSNI-2011
• Brand: Biosynth
• Description: Cevimeline hydrochloride salt is a cholinergic drug that activates the muscarinic receptors in the salivary glands. It has been used for the treatment of dry mouth and xerostomia in patients with Sjögren's syndrome, diabetes, or following radiation therapy. Cevimeline hydrochloride has been shown to increase the production of saliva in animal models of Sjögren's syndrome by stimulating cAMP-dependent protein kinase A (PKA) activity. This drug also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. Cevimeline hydrochloride salt can cause side effects such as eye disorders, skin cancer, and geriatric patients with adenosine A3 receptor antagonists. Benzalkonium chloride is an ingredient in cevimeline hydrochloride salt that acts as a preservative and antimicrobial agent.

Chemical properties

• Molecular weight: 235.77 g/mol
• Formula: C₁₀H₁₇NOS•HCl
• Purity: Min. 95%
• Color/Form: Powder