Clozapine N-oxide

CAS: 34233-69-7

Ref. 3D-FC20527

Product Information

• Name: Clozapine N-oxide
• Synonyms: 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine N-oxide
• Brand: Biosynth
• Description: Activates muscarinic GPCR DREADDs, which are unaffected by the endogenous ligand acetycholamine of the parent receptor. Clozapine is metabolized to clozapine N oxide in the liver, mainly by CYP3A4. Has anti-seizure effects, when induced by chemoconvulsants pilocarpine and picrotoxin.

Chemical properties

• Molecular weight: 342.82 g/mol
• Formula: C₁₈H₁₉ClN₄O
• Purity: Min. 99 Area-%
• Color/Form: Yellow Powder