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Cyclopamine

CAS:

Ref. 3D-FC20718

25mg
135.00€
100mg
240.00€
250mg
469.00€
500mg
668.00€
Cyclopamine
Biosynth

Product Information

Name:Cyclopamine
Synonyms:
  • (2′R,3S,3′R,3′aS,6′S,6aS,6bS,7′aR,11aS,11bR)-1,2,3,3′a,4,4′,5′,6,6′,6a,6b,7,7′,7′a,8,11,11a,11b-Octadecahydro-3′,6′,10,11b-tetrameth ylspiro[9H-benzo[a]fluorene-9,2′(3′H)-furo[3,2-b]pyridin]-3-ol
Brand:Biosynth
Description:Inhibitor of the Smoothened receptor and Hedgehog signalling pathway. Cyclopamine is a steroidal alkaloid that binds to the heptahelical bundle of Smoothened and negatively regulates transcription of downstream genes. In prostate cancer cells, cyclopamine inhibited cell growth, arrested cell cycle and in glioblastoma, it depleted stem cell-like cancer cells.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:411.62 g/mol
Formula:C27H41NO2
Purity:Min. 95%
Color/Form:White Solid

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