Vismodegib
CAS: 879085-55-9
Ref. 3D-FC28712
1g | 378.00 € | ||
5g | 1,015.00 € | ||
10g | 1,739.00 € | ||
250mg | 172.00 € | ||
500mg | 271.00 € |
Product Information
- GDC 04492-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
- 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
- Benzamide, 2-Chloro-N-[4-Chloro-3-(2-Pyridinyl)Phenyl]-4-(Methylsulfonyl)-
- Erivedge
- Gdc-0449
- Vismodegib (GDC-0449)
Vismodegib is a Hedgehog (Hh) pathway inhibitor belonging to the 2-arylpyridine class. It acts as a competitive antagonist of the smoothened receptor (SMO) localized in the cell membrane. SMO activates an intracellular cascade that results in activation and nuclear translocation of Gli family transcription factor. Vismodegib has been used in clinical trials for treatment of advanced cancers.
Chemical properties
Technical inquiry about: 3D-FC28712 Vismodegib
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