Product Information
Name:Vismodegib
Synonyms:
- GDC 04492-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
Brand:Biosynth
Description:Vismodegib is a Hedgehog (Hh) pathway inhibitor belonging to the 2-arylpyridine class. It acts as a competitive antagonist of the smoothened receptor (SMO) localized in the cell membrane. SMO activates an intracellular cascade that results in activation and nuclear translocation of Gli family transcription factor. Vismodegib has been used in clinical trials for treatment of advanced cancers.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:421.30 g/mol
Formula:C19H14Cl2N2O3S
Purity:Min. 95%
Color/Form:Powder
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