Cbz-L-glutamine

CAS: 2650-64-8

Ref. 3D-FC39401

Product Information

• Name: Cbz-L-glutamine
• Synonyms: (2S)-2-[[(Benzyloxy)carbonyl]amino]-4-carbamoylbutanoic acid, (2S)-5-Amino-5-oxo-2-(phenylmethoxycarbonylamino)pentanoic acid, (2S)-5-amino-2-{[(benzyloxy)carbonyl]amino}-5-oxopentanoate, <span class="text-smallcaps">L</span>-Glutamine, N²-[(phenylmethoxy)carbonyl]-, Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-glutamine, BenzyloxycarbonylLglutamine, Carbobenzoxy-<span class="text-smallcaps">L</span>-glutamine, Cbz-<span class="text-smallcaps">L</span>-glutamine, Cbz-Gln-OH, Glutamine, N²-carboxy-, N-benzyl ester, Glutamine, N²-carboxy-, N²-benzyl ester, <span class="text-smallcaps">L</span>-, N(alpha)-Benzyloxycarbonyl-L-glutamine, N(alpha)-Cbz-L-glutamine, N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-glutamine, N-Carbobenzoxy-<span class="text-smallcaps">L</span>-glutamine, N-cbz-L-glutamine crystalline, N2-[(benzyloxy)carbonyl]-L-glutamine, N2-[(benzyloxy)carbonyl]glutamine, N²-Benzoxycarbonyl-<span class="text-smallcaps">L</span>-glutamine, N²-Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-glutamine, N²-Carbobenzoxy-<span class="text-smallcaps">L</span>-glutamine, N²-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-glutamine, N^α-Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-glutamine, NSC 186903, Z-Gln-OH, Z-L-Glutamine, z-Gln
• CAS: 2650-64-8

Description

Cbz-L-glutamine is a water soluble compound that is used in the synthesis of pomalidomide. It is synthesized through a stepwise amide formation from methylamine and ethylene diamine. Cbz-L-glutamine has been shown to have an inhibitory effect on cancer cells, which may be due to its ability to break down hydroxamic acids. This chemical reaction causes the release of hydrogen ions, which leads to the disruption of various cellular processes, such as DNA replication and protein synthesis. The uptake of Cbz-L-glutamine by cancer cells has been shown in tissue culture experiments.

• Brand: Biosynth

Chemical properties

• Molecular weight: 280.28 g/mol
• Formula: C₁₃H₁₆N₂O₅
• Purity: Min. 95%
• Color/Form: Powder